Detecting Protein Function and Protein-Protein Interactions from Genome Sequences
نویسندگان
چکیده
منابع مشابه
Detecting protein function and protein-protein interactions from genome sequences.
A computational method is proposed for inferring protein interactions from genome sequences on the basis of the observation that some pairs of interacting proteins have homologs in another organism fused into a single protein chain. Searching sequences from many genomes revealed 6809 such putative protein-protein interactions in Escherichia coli and 45,502 in yeast. Many members of these pairs ...
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ژورنال
عنوان ژورنال: Science
سال: 1999
ISSN: 0036-8075,1095-9203
DOI: 10.1126/science.285.5428.751